This book provides an overview of nanoparticulate drug delivery systems, their potential applications and limitations. The chapters focus on new approaches, manufacturing methodologies, and applications of nanotechnology in drug delivery. Chapter 1 provides an overview of targeted nanomedicine and ddresses strategies developed to overcome limitations of existing systems. It covers a variety of specific topics like dendrimer-based drug delivery, the new liposome system, polymeric nanoparticle systems, and nanocrystals. Part 2 covers preclinical and clinical applications of nanoparticulate systems that have identified their new potentials or biological barriers interfering with the delivery. Each chapter reviews state-of-the-art topics, includes extensive references, and assesses challenges in the field. Overall, this book delivers up-to-date information on nanoparticulate drug delivery systems for students, researchers and professionals in the pharmaceutical, biomedical engineering, and related health sciences industries.